- BUSCOPAN Injectable Solution is an antispasmodic (spasmolytic) and anticholinergic drug used for the control of abdominal pain (colic) in horses. Colic is a common and distressing condition that can range from mild discomfort to severe pain. It often results from spasms in the gastrointestinal tract, which can lead to colonic impactions or gas accumulation.
- Here’s a detailed overview of BUSCOPAN’s properties and its role in managing equine colic:
- Mechanism of Action:
- BUSCOPAN contains the active ingredient N-butylscopolammonium bromide, which acts by relaxing smooth muscles in the gastrointestinal tract. It specifically targets the muscarinic receptors, inhibiting the action of acetylcholine and reducing spasms.
- By suppressing spasms, BUSCOPAN helps alleviate abdominal pain and discomfort in horses.
- Fast Relief:
- When administered intravenously, BUSCOPAN starts acting within 5–10 minutes.
- Most horses respond positively to treatment within 30 minutes, experiencing relief from painful colic spasms.
- In clinical studies, 88 percent of colic horses evaluated were successfully relieved of colic spasms within this timeframe.
- Effective Relief and Behavioral Improvement:
- Behavioral-attitude scores improve significantly after treatment.
- Total colic scores decrease, indicating effective relief.
- Horses become more alert and calm, reflecting their improved well-being.
- Safety Considerations:
- BUSCOPAN should not be used in impaction colics associated with ileus or in horses with glaucoma.
- Effects may be potentiated when used with other anticholinergic drugs.
- Safe use in nursing foals, pregnant, or lactating mares has not been established.
- Transient elevated heart rate is a common side effect after injection.
- Overall Benefit:
- BUSCOPAN provides rapid and targeted relief, allowing horses to recover from colic episodes more comfortably.
- Veterinarians rely on BUSCOPAN to manage colic effectively.
- Mechanism of Action:
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